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Fatty acid activated PPARγ promotes tumorigenicity of prostate cancer cells by up regulating VEGF via PPAR responsive elements of the promoter

In previous work, it is suggested that the excessive amount of fatty acids transported by FABP5 may facilitate the malignant progression of prostate cancer cells through a FABP5-PPARγ-VEGF signal transduction axis to increase angiogenesis. To further functionally characterise the FABP5-PPARγ-VEGF si...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Forootan, Farzad S., Forootan, Shiva S., Gou, Xiaojun, Yang, Jin, Liu, Bichong, Chen, Danqing, Fayi, Majed Saad Al, Al-Jameel, Waseem, Rudland, Philip S., Hussain, Syed A., Ke, Youqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891043/
https://ncbi.nlm.nih.gov/pubmed/26814431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6975
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