Fatty acid activated PPARγ promotes tumorigenicity of prostate cancer cells by up regulating VEGF via PPAR responsive elements of the promoter

In previous work, it is suggested that the excessive amount of fatty acids transported by FABP5 may facilitate the malignant progression of prostate cancer cells through a FABP5-PPARγ-VEGF signal transduction axis to increase angiogenesis. To further functionally characterise the FABP5-PPARγ-VEGF si...

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Udgivet i:Oncotarget
Main Authors: Forootan, Farzad S., Forootan, Shiva S., Gou, Xiaojun, Yang, Jin, Liu, Bichong, Chen, Danqing, Fayi, Majed Saad Al, Al-Jameel, Waseem, Rudland, Philip S., Hussain, Syed A., Ke, Youqiang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891043/
https://ncbi.nlm.nih.gov/pubmed/26814431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6975
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