MGMT Promoter Methylation and BRAF V600E Mutations Are Helpful Markers to Discriminate Pleomorphic Xanthoastrocytoma from Giant Cell Glioblastoma

Giant Cell Glioblastoma (gcGBM) and Pleomorphic Xanthoastrocytoma (PXA) are rare astroglial tumors of the central nervous system. Although they share certain histomorphological and immunohistochemical features, they are characterized by different clinical behavior and prognosis. Nevertheless, few ca...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lohkamp, Laura-Nanna, Schinz, Maren, Gehlhaar, Claire, Guse, Katrin, Thomale, Ulrich-Wilhelm, Vajkoczy, Peter, Heppner, Frank L., Koch, Arend
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890800/
https://ncbi.nlm.nih.gov/pubmed/27253461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156422
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