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Analysis of Local Molecular Motions of Aromatic Sidechains in Proteins by 2D and 3D Fast MAS NMR Spectroscopy and Quantum Mechanical Calculations

We report a new multidimensional magic angle spinning NMR methodology, which provides an accurate and detailed probe of molecular motions occurring on timescales of nano- to microseconds, in sidechains of proteins. The approach is based on a 3D CPVC-RFDR correlation experiment recorded under fast MA...

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Detalhes bibliográficos
Publicado no:Phys Chem Chem Phys
Main Authors: Paluch, Piotr, Pawlak, Tomasz, Jeziorna, Agata, Trébosc, Julien, Hou, Guangjin, Vega, Alexander J., Amoureux, Jean-Paul, Dracinsky, Martin, Polenova, Tatyana, Potrzebowski, Marek J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890705/
https://ncbi.nlm.nih.gov/pubmed/26451400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cp04475h
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