A role for PDGF-C/PDGFRα signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex

Platelet-derived growth factor-C (PDGF-C) is one of three known ligands for the tyrosine kinase receptor PDGFRα. Analysis of Pdgfc null mice has demonstrated roles for PDGF-C in palate closure and the formation of cerebral ventricles, but redundancy with other PDGFRα ligands might obscure additional...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Andrae, Johanna, Gouveia, Leonor, Gallini, Radiosa, He, Liqun, Fredriksson, Linda, Nilsson, Ingrid, Johansson, Bengt R., Eriksson, Ulf, Betsholtz, Christer
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890675/
https://ncbi.nlm.nih.gov/pubmed/26988758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.017368
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