Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort

We examined whether persistence of epigenetic DNA methylation (DNA-me) alterations at specific loci over two different time points in people with diabetes are associated with metabolic memory, the prolonged beneficial effects of intensive vs. conventional therapy during the Diabetes Control and Comp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Zhuo, Miao, Feng, Paterson, Andrew D., Lachin, John M., Zhang, Lingxiao, Schones, Dustin E., Wu, Xiwei, Wang, Jinhui, Tompkins, Joshua D., Genuth, Saul, Braffett, Barbara H., Riggs, Arthur D., Natarajan, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890596/
https://ncbi.nlm.nih.gov/pubmed/27162351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603712113
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