MicroRNA-125b: association with disease activity and the treatment response of patients with early rheumatoid arthritis

BACKGROUND: MicroRNAs (miRNAs) are small RNAs that regulate gene expression by targeting mRNA. It was proved that some miRNAs are significantly deregulated in rheumatoid arthritis (RA). MicroRNA-125b negatively regulates expression of TNF-α, which plays a crucial role in RA pathogenesis. The aim of...

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Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Hruskova, Veronika, Jandova, Romana, Vernerova, Lucia, Mann, Herman, Pecha, Ondrej, Prajzlerova, Klara, Pavelka, Karel, Vencovsky, Jiri, Filkova, Maria, Senolt, Ladislav
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890522/
https://ncbi.nlm.nih.gov/pubmed/27255643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1023-0
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