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QbD-Driven Development and Validation of a Bioanalytical LC–MS Method for Quantification of Fluoxetine in Human Plasma
The current studies describe the Quality by Design (QbD)-based development and validation of a LC–MS-MS method for quantification of fluoxetine in human plasma using fluoxetine-D5 as an internal standard (IS). Solid-phase extraction was employed for sample preparation, and linearity was observed for...
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| Publicado no: | J Chromatogr Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4890445/ https://ncbi.nlm.nih.gov/pubmed/26860396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chromsci/bmv248 |
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