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A Validated Stability-Indicating and Stereoselective HPLC Method for the Determination of Lenalidomide Enantiomers in Bulk Form and Capsules

A simple, rapid and stability-indicating chiral HPLC (CHR-HPLC) method was designed for the enantiomeric separation of lenalidomide (LDM) in the presence of its degradation products. LDM was exposed to different accelerated stress factors. The degradation products were well resolved from the pure dr...

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Publicat a:J Chromatogr Sci
Autor principal: Alzoman, Nourah Z.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890444/
https://ncbi.nlm.nih.gov/pubmed/26850732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chromsci/bmv247
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