Simultaneous Determination and Pharmacokinetic Study of Protocatechuic Aldehyde and Its Major Active Metabolite Protocatechuic Acid in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry

A very simple and selective high-performance liquid chromatography electrospray ionization tandem mass spectrometry (LC–MS-MS) method was developed for simultaneous determination and pharmacokinetic study of protocatechuic aldehyde (PAL) and its active metabolite protocatechuic acid (PCA). The metho...

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Detalhes bibliográficos
Publicado no:J Chromatogr Sci
Main Authors: Wang, Xiangyang, Yan, Kaijing, Ma, Xiaohui, Li, Wei, Chu, Yang, Guo, Jiahua, Li, Shuming, Zhou, Shuiping, Zhu, Yonghong, Liu, Changxiao
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Liquid Chromatography
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890439/
https://ncbi.nlm.nih.gov/pubmed/26969682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chromsci/bmv240
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