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IgA production requires B cell interaction with subepithelial dendritic cells in Peyer’s patches
Immunoglobulin A (IgA) induction primarily occurs in intestinal Peyer’s patches (PPs). However, the cellular interactions necessary for IgA class switching are poorly defined. Here we show that in mice, activated B cells use the chemokine receptor CCR6 to access the sup-epithelial dome (SED) of PPs....
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4890166/ https://ncbi.nlm.nih.gov/pubmed/27174992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf4822 |
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