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MicroRNA-449a enhances radiosensitivity by downregulation of c-Myc in prostate cancer cells

MicroRNAs (miRNAs) have been reported to be involved in DNA damage response induced by ionizing radiation (IR). c-Myc is reduced when cells treated with IR or other DNA damaging agents. It is unknown whether miRNAs participate in c-Myc downregulation in response to IR. In the present study, we found...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mao, Aihong, Zhao, Qiuyue, Zhou, Xin, Sun, Chao, Si, Jing, Zhou, Rong, Gan, Lu, Zhang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890029/
https://ncbi.nlm.nih.gov/pubmed/27250340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27346
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