Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine

The long noncoding RNA Gomafu/MIAT/Rncr2 is thought to function in retinal cell specification, stem cell differentiation and the control of alternative splicing. To further investigate physiological functions of Gomafu, we created mouse knockout (KO) model that completely lacks the Gomafu gene. The...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ip, Joanna Y., Sone, Masamitsu, Nashiki, Chieko, Pan, Qun, Kitaichi, Kiyoyuki, Yanaka, Kaori, Abe, Takaya, Takao, Keizo, Miyakawa, Tsuyoshi, Blencowe, Benjamin J., Nakagawa, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890022/
https://ncbi.nlm.nih.gov/pubmed/27251103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27204
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