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Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome
Cisplatin is a widely prescribed anticancer drug, which triggers cell death by covalent binding to a broad range of biological molecules. Among cisplatin targets, cellular RNAs remain the most poorly characterized molecules. Although cisplatin was shown to inactivate essential RNAs, including riboso...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889946/ https://ncbi.nlm.nih.gov/pubmed/27079977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw246 |
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