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CSF/plasma HIV-1 RNA discordance even at low levels is associated with up-regulation of host inflammatory mediators in CSF()

INTRODUCTION: HIV-1 RNA can be found at higher levels in cerebrospinal fluid (CSF) than in plasma, termed CSF/plasma discordance. The clinical significance of CSF/plasma discordance is not known and the degree of discordance considered important varies. We aimed to determine whether a panel of CSF c...

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Detalhes bibliográficos
Publicado no:Cytokine
Main Authors: Nightingale, Sam, Michael, Benedict D., Fisher, Martin, Winston, Alan, Nelson, Mark, Taylor, Steven, Ustianowski, Andrew, Ainsworth, Jonathan, Gilson, Richard, Haddow, Lewis, Ong, Edmund, Leen, Clifford, Minton, Jane, Post, Frank, Beloukas, Apostolos, Borrow, Ray, Pirmohamed, Munir, Geretti, Anna Maria, Khoo, Saye, Solomon, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889775/
https://ncbi.nlm.nih.gov/pubmed/27131579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2016.04.004
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