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Elevation of plasma phenytoin by viloxazine in epileptic patients: a clinically significant drug interaction.

The effect of viloxazine (150-300 mg daily for 21 days) on plasma phenytoin levels at steady state was examined in 10 epileptic patients stabilised on a fixed phenytoin dosage. After starting viloxazine treatment, plasma phenytoin concentrations increased by 37% on average (range 7-94%) from a mean...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurol Neurosurg Psychiatry
Hauptverfasser: Pisani, F, Fazio, A, Artesi, C, Russo, M, Trio, R, Oteri, G, Perucca, E, Di Perri, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC488975/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1538217/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jnnp.55.2.126
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