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Interconnections Between RNA-Processing Pathways Revealed by a Sequencing-Based Genetic Screen for Pre-mRNA Splicing Mutants in Fission Yeast

Pre-mRNA splicing is an essential component of eukaryotic gene expression and is highly conserved from unicellular yeasts to humans. Here, we present the development and implementation of a sequencing-based reverse genetic screen designed to identify nonessential genes that impact pre-mRNA splicing...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Larson, Amy, Fair, Benjamin Jung, Pleiss, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889648/
https://ncbi.nlm.nih.gov/pubmed/27172183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.027508
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