Atg5 is essential for the development and survival of innate lymphocytes

Autophagy is an essential cellular survival mechanism that is required for adaptive lymphocyte development; however, its role in innate lymphoid cell (ILC) development remains unknown. Furthermore, the conditions that promote lymphocyte autophagy during homeostasis are poorly understood. Here we dem...

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Veröffentlicht in:Cell Rep
Hauptverfasser: O’Sullivan, Timothy E., Geary, Clair D., Weizman, Orr-El, Geiger, Theresa L., Rapp, Moritz, Dorn, Gerald W., Overholtzer, Michael, Sun, Joseph C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889506/
https://ncbi.nlm.nih.gov/pubmed/27210760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.082
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