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PLCζ sequence, protein levels, and distribution in human sperm do not correlate with semen characteristics and fertilization rates after ICSI

PURPOSE: Sperm-borne PLCζ protein induces Ca(2+) oscillations in the oocyte and is believed to play a major role during oocyte activation. However, its implication in fertilization failure following ICSI is still debated. We analyzed PLCζ gene sequence, protein expression level, and localization in...

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Bibliographische Detailangaben
Veröffentlicht in:J Assist Reprod Genet
Hauptverfasser: Ferrer-Vaquer, Anna, Barragan, Montserrat, Freour, Thomas, Vernaeve, Valérie, Vassena, Rita
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889489/
https://ncbi.nlm.nih.gov/pubmed/27138933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-016-0718-0
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