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Expansion of myeloid-derived suppressor cells promotes differentiation of regulatory T cells in HIV-1(+) individuals

OBJECTIVE: Regulatory T cells (Tregs) contribute to HIV-1 disease progression by impairing antiviral immunity; however, the precise mechanisms responsible for the development of Tregs in the setting of HIV-1 infection are incompletely understood. DESIGN: In this study, we provide evidence that HIV-i...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: Wang, Ling, Zhao, Juan, Ren, Jun P., Wu, Xiao Y., Morrison, Zheng D., Elgazzar, Mohamed A, Ning, Shun B., Moorman, Jonathan P., Yao, Zhi Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889474/
https://ncbi.nlm.nih.gov/pubmed/26959508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001083
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