Exogenous nitric oxide inhibits Rho-associated kinase activity in patients with angina pectoris: a randomized controlled trial

The RhoA/Rho-associated kinase (ROCK) pathway has a key physiological role in the pathogenesis of atherosclerosis. Increased ROCK activity is associated with cardiovascular diseases. Endogenous nitric oxide (NO) has an anti-atherosclerotic effect, whereas the exogenous NO-mediated cardiovascular eff...

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Vydáno v:Hypertens Res
Hlavní autoři: Maruhashi, Tatsuya, Noma, Kensuke, Fujimura, Noritaka, Kajikawa, Masato, Matsumoto, Takeshi, Hidaka, Takayuki, Nakashima, Ayumu, Kihara, Yasuki, Liao, James K, Higashi, Yukihito
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889444/
https://ncbi.nlm.nih.gov/pubmed/25740292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2015.24
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