PDK1–Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex

Neurons migrate a long radial distance by a process known as locomotion in the developing mammalian neocortex. During locomotion, immature neurons undergo saltatory movement along radial glia fibers. The molecular mechanisms that regulate the speed of locomotion are largely unknown. We now show that...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Itoh, Yasuhiro, Higuchi, Maiko, Oishi, Koji, Kishi, Yusuke, Okazaki, Tomohiko, Sakai, Hiroshi, Miyata, Takaki, Nakajima, Kazunori, Gotoh, Yukiko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889351/
https://ncbi.nlm.nih.gov/pubmed/27170189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516321113
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