Autophagy protects ovarian cancer-associated fibroblasts against oxidative stress

RNA-Seq and gene set enrichment anylysis revealed that ovarian cancer associated fibroblasts (CAFs) are mitotically active compared with normal fibroblasts (NFs). Cellular senescence is observed in CAFs treated with H(2)O(2) as shown by elevated SA-β-gal activity and p21 (WAF1/Cip1) protein levels....

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Wang, Qian, Xue, Liang, Zhang, Xiaoyu, Bu, Shixia, Zhu, Xueliang, Lai, Dongmei
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889272/
https://ncbi.nlm.nih.gov/pubmed/27074587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1170269
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