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Critical reanalysis of the methods that discriminate the activity of CDK2 from CDK1

Cyclin dependent kinases 1 and 2 (CDK1 and CDK2) play crucial roles in regulating cell cycle progression from G1 to S, through S, and G2 to M phase. Both inhibition and aberrant activation of CDK1/2 can be detrimental to cancer cell growth. However, the tools routinely employed to discriminate betwe...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Sakurikar, Nandini, Eastman, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889245/
https://ncbi.nlm.nih.gov/pubmed/26986210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1160983
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