Variant Aldehyde Dehydrogenase 2 (ALDH2*2) Is a Risk Factor for Coronary Spasm and ST‐Segment Elevation Myocardial Infarction

BACKGROUND: Mitochondrial aldehyde dehydrogenase 2 (ALDH2) plays a key role in removing toxic aldehydes. Deficient variant ALDH2*2 genotype is prevalent in up to 40% of the East Asians and reported to be associated with acute myocardial infarction (AMI). To elucidate the mechanisms underlying the as...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Mizuno, Yuji, Hokimoto, Seiji, Harada, Eisaku, Kinoshita, Kenji, Nakagawa, Kazuko, Yoshimura, Michihiro, Ogawa, Hisao, Yasue, Hirofumi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889196/
https://ncbi.nlm.nih.gov/pubmed/27153870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003247
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