Role of Mitochondrial Oxidative Stress in Glucose Tolerance, Insulin Resistance, and Cardiac Diastolic Dysfunction

BACKGROUND: Diabetes mellitus (DM) is associated with mitochondrial oxidative stress. We have shown that myocardial oxidative stress leads to diastolic dysfunction in a hypertensive mouse model. Therefore, we hypothesized that diabetes mellitus could cause diastolic dysfunction through mitochondrial...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Jeong, Euy‐Myoung, Chung, Jaehoon, Liu, Hong, Go, Yeongju, Gladstein, Scott, Farzaneh‐Far, Afshin, Lewandowski, E. Douglas, Dudley, Samuel C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889180/
https://ncbi.nlm.nih.gov/pubmed/27151515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.003046
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