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Exploiting the epigenome to control cancer promoting gene expression programs

The epigenome is a key determinant of transcriptional output. Perturbations within the epigenome are thought to be a key feature of many, perhaps all cancers, and it is now clear that epigenetic changes are instrumental in cancer development. The inherent reversibility of these changes makes them at...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Brien, Gerard L., Valerio, Daria G., Armstrong, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889129/
https://ncbi.nlm.nih.gov/pubmed/27070701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.03.007
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