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High Levels of Sample-to-Sample Variation Confound Data Analysis for Non-Invasive Prenatal Screening of Fetal Microdeletions

Our goal was to test the hypothesis that inter-individual genomic copy number variation in control samples is a confounding factor in the non-invasive prenatal detection of fetal microdeletions via the sequence-based analysis of maternal plasma DNA. The database of genomic variants (DGV) was used to...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Chu, Tianjiao, Yeniterzi, Suveyda, Yatsenko, Svetlana A., Dunkel, Mary, Shaw, Patricia A., Bunce, Kimberly D., Peters, David G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889033/
https://ncbi.nlm.nih.gov/pubmed/27249650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153182
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