Three-dimensional characterization of fibroblast foci in idiopathic pulmonary fibrosis

In idiopathic pulmonary fibrosis (IPF), the fibroblast focus is a key histological feature representing active fibroproliferation. On standard 2D pathologic examination, fibroblast foci are considered small, distinct lesions, although they have been proposed to form a highly interconnected reticulum...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Jones, Mark G., Fabre, Aurélie, Schneider, Philipp, Cinetto, Francesco, Sgalla, Giacomo, Mavrogordato, Mark, Jogai, Sanjay, Alzetani, Aiman, Marshall, Ben G., O’Reilly, Katherine M.A., Warner, Jane A., Lackie, Peter M., Davies, Donna E., Hansell, David M., Nicholson, Andrew G., Sinclair, Ian, Brown, Kevin K., Richeldi, Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889020/
https://ncbi.nlm.nih.gov/pubmed/27275013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86375
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