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Acrolein-mediated conduction loss is partially restored by K(+) channel blockers
Acrolein-mediated myelin damage is thought to be a critical mechanism leading to conduction failure following neurotrauma and neurodegenerative diseases. The exposure and activation of juxtaparanodal voltage-gated K(+) channels due to myelin damage leads to conduction block, and K(+) channel blocker...
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| Publicado no: | J Neurophysiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888969/ https://ncbi.nlm.nih.gov/pubmed/26581866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00467.2015 |
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