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Interferon‐beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization

Age‐related macular degeneration (AMD) is a leading cause of vision loss among the elderly. AMD pathogenesis involves chronic activation of the innate immune system including complement factors and microglia/macrophage reactivity in the retina. Here, we show that lack of interferon‐β signaling in th...

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Bibliografiska uppgifter
I publikationen:EMBO Mol Med
Huvudupphovsmän: Lückoff, Anika, Caramoy, Albert, Scholz, Rebecca, Prinz, Marco, Kalinke, Ulrich, Langmann, Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888856/
https://ncbi.nlm.nih.gov/pubmed/27137488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505994
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