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Design and evaluation of novel oxadiazole derivatives as potential prostate cancer agents

Various 1,3,4-oxadiazole derivatives have been synthesized and their antiproliferative properties have been studied. The in vitro screening was performed against androgen dependent (LNCaP) and androgen independent (PC-3) prostate cancer cell lines. Most of the compounds showed promising activity. Am...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Mochona, Bereket, Qi, Xin, Euynni, Suresh, Sikazwi, Donald, Mateeva, Nelly, Soliman, Karam F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888807/
https://ncbi.nlm.nih.gov/pubmed/27156770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.04.058
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