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Development of a dot blot assay with antibodies to recombinant “core” 14-3-3 protein: Evaluation of its usefulness in diagnosis of Creutzfeldt–Jakob disease

BACKGROUND AND PURPOSE: Definitive diagnosis of Creutzfeldt–Jakob disease (CJD) requires demonstration of infective prion protein (PrP(Sc)) in brain tissues by immunohistochemistry or immunoblot, making antemortem diagnosis of CJD difficult. The World Health Organization (WHO) recommends detection o...

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Detalhes bibliográficos
Publicado no:Ann Indian Acad Neurol
Main Authors: Subramanian, Sarada, Mahadevan, Anita, Satishchandra, Parthasarathy, Shankar, Susarla Krishna
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888683/
https://ncbi.nlm.nih.gov/pubmed/27293331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0972-2327.176867
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