Reduced levels of alpha-1-antitrypsin in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a novel approach for a potential treatment

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative motor neuron disease that involves activation of the immune system and inflammatory response in the nervous system. Reduced level of the immuno-modulatory and anti-inflammatory protein alpha-1-antitrypsin (AAT) is asso...

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Publicat a:J Neuroinflammation
Autors principals: Wormser, Uri, Mandrioli, Jessica, Vinceti, Marco, Fini, Nicola, Sintov, Amnon, Brodsky, Berta, Proskura, Elena, Finkelstein, Yoram
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888657/
https://ncbi.nlm.nih.gov/pubmed/27245439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0589-4
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