Herbal formula GAPT prevents beta amyloid deposition induced Ca(2+)/Calmodulin-dependent protein kinase II and Ca(2+)/Calmodulin-dependent protein phosphatase 2B imbalance in APPV717I mice

BACKGROUND: Synaptic dysfunction is one of the pathological characteristics of Alzheimer's disease (AD), which is directly related to the progressive decline of cognitive function. CaMKII and CaN have been found to play important roles in memory processes and synaptic transmission. So present s...

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Publicado en:BMC Complement Altern Med
Autores principales: Shi, Jing, Zhang, Xuekai, Yin, Long, Wei, Mingqing, Ni, Jingnian, Li, Ting, Wang, Pengwen, Tian, Jinzhou, Wang, Yongyan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888629/
https://ncbi.nlm.nih.gov/pubmed/27245225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-016-1144-7
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