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Impact of nitric-oxide-mediated vasodilation and oxidative stress on renal medullary oxygenation: a modeling study

The goal of this study was to investigate the effects of nitric oxide (NO)-mediated vasodilation in preventing medullary hypoxia, as well as the likely pathways by which superoxide (O(2)(−)) conversely enhances medullary hypoxia. To do so, we expanded a previously developed mathematical model of sol...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Fry, Brendan C., Edwards, Aurélie, Layton, Anita T.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888562/
https://ncbi.nlm.nih.gov/pubmed/26831340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00334.2015
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