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Optogenetic activation of mechanically insensitive afferents in mouse colorectum reveals chemosensitivity
The sensory innervation of the distal colorectum includes mechanically insensitive afferents (MIAs; ∼25%), which acquire mechanosensitivity in persistent visceral hypersensitivity and thus generate de novo input to the central nervous system. We utilized an optogenetic approach to bypass the process...
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| Publicado no: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888546/ https://ncbi.nlm.nih.gov/pubmed/26950857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00430.2015 |
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