Loss of HGF activator inhibits foveolar hyperplasia induced by oxyntic atrophy without altering gastrin levels

Spasmolytic polypeptide/trefoil family factor 2 expressing metaplasia (SPEM) is induced by oxyntic atrophy and is known as a precancerous or paracancerous lesion. We now have sought to determine whether hepatocyte growth factor (HGF) influences the development of SPEM and oxyntic atrophy. DMP-777, a...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Yamagata, Yukinori, Aikou, Susumu, Fukushima, Tsuyoshi, Kataoka, Hiroaki, Seto, Yasuyuki, Esumi, Hiroyasu, Kaminishi, Michio, Goldenring, James R., Nomura, Sachiyo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
Hormones and Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888532/
https://ncbi.nlm.nih.gov/pubmed/23064758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00107.2012
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