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Modeling analysis of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) mobilization under the control of glucagon-like peptide-1 in mouse pancreatic β-cells
Glucagon-like peptide-1 (GLP-1) is an intestinally derived blood glucose-lowering hormone that potentiates glucose-stimulated insulin secretion from pancreatic β-cells. The secretagogue action of GLP-1 is explained, at least in part, by its ability to stimulate cAMP production so that cAMP may facil...
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Publicado no: | Am J Physiol Cell Physiol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888524/ https://ncbi.nlm.nih.gov/pubmed/26741144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00234.2015 |
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