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Modeling analysis of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) mobilization under the control of glucagon-like peptide-1 in mouse pancreatic β-cells

Glucagon-like peptide-1 (GLP-1) is an intestinally derived blood glucose-lowering hormone that potentiates glucose-stimulated insulin secretion from pancreatic β-cells. The secretagogue action of GLP-1 is explained, at least in part, by its ability to stimulate cAMP production so that cAMP may facil...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Takeda, Yukari, Shimayoshi, Takao, Holz, George G., Noma, Akinori
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888524/
https://ncbi.nlm.nih.gov/pubmed/26741144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00234.2015
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