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Inheritance of the CENP-A chromatin domain is spatially and temporally constrained at human centromeres

BACKGROUND: Chromatin containing the histone variant CENP-A (CEN chromatin) exists as an essential domain at every centromere and heritably marks the location of kinetochore assembly. The size of the CEN chromatin domain on alpha satellite DNA in humans has been shown to vary according to underlying...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Ross, Justyne E., Woodlief, Kaitlin Stimpson, Sullivan, Beth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888493/
https://ncbi.nlm.nih.gov/pubmed/27252782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0071-7
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