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Notoginsenoside Rb1 inhibits activation of ERK and p38 MAPK pathways induced by hypoxia and hypercapnia

The aim of the present study was to investigate the effect of notoginsenoside Rb1 (Rb1) on the ERK and p38 MAPK pathways in primary cultured pulmonary arterial smooth muscle cells (PASMCs) exposed to hypoxia and hypercapnia, in order to elucidate the mechanism underlying the effect of Rb1 on hypoxia...

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Détails bibliographiques
Publié dans:Exp Ther Med
Auteurs principaux: QIU, XIAOXIAO, ZHENG, MENGXIAO, SONG, DONG, HUANG, LINJING, TANG, LANLAN, YING, LEI, WANG, WANTIE
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888033/
https://ncbi.nlm.nih.gov/pubmed/27313674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3217
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