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Outer‐sphere residues influence the catalytic activity of a chalcone synthase from Polygonum cuspidatum

We have previously cloned a chalcone synthase (PcCHS1) from Polygonum cuspidatum and biochemically identified its enzymatic dynamic properties. Here, we found that the outer sphere residues, Q82 and R105, could affect the catalytic activity and product profile of PcCHS1. Both Q82P and R105Q mutation...

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Dettagli Bibliografici
Pubblicato in:FEBS Open Bio
Autori principali: Shen, Yalin, Li, Xing, Chai, Tuanyao, Wang, Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887977/
https://ncbi.nlm.nih.gov/pubmed/27419064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12072
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