A light-controlled switch after dual targeting of proliferating tumor cells via the membrane receptor EGFR and the nuclear protein Ki-67

Using nanotechnology for optical manipulation of molecular processes in cells with high spatial and temporal precision promises new therapeutic options. Especially tumor therapy may profit as it requires a combination of both selectivity and an effective cell killing mechanism. Here we show a dual t...

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Vydáno v:Sci Rep
Hlavní autoři: Wang, Sijia, Hüttmann, Gereon, Scholzen, Thomas, Zhang, Zhenxi, Vogel, Alfred, Hasan, Tayyaba, Rahmanzadeh, Ramtin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887907/
https://ncbi.nlm.nih.gov/pubmed/27246531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27032
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