Paeoniflorin inhibits doxorubicin-induced cardiomyocyte apoptosis by downregulating microRNA-1 expression

Doxorubicin (DOX) is an effective anthracycline anti-tumor antibiotic. Because of its cardiotoxicity, the clinical application of DOX is limited. Paeoniflorin (PEF), a monoterpene glucoside extracted from the dry root of Paeonia, is reported to exert multiple beneficial effects on the cardiovascular...

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Publicat a:Exp Ther Med
Autors principals: LI, JIAN-ZHE, TANG, XIU-NENG, LI, TING-TING, LIU, LI-JUAN, YU, SHU-YI, ZHOU, GUANG-YU, SHAO, QING-RUI, SUN, HUI-PING, WU, CHENG, YANG, YANG
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887841/
https://ncbi.nlm.nih.gov/pubmed/27284328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3182
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