Nanopharmaceutical Approach for Enhanced Anti-cancer Activity of Betulinic Acid in Lung-cancer Treatment via Activation of PARP: Interaction with DNA as a Target: -Anti-cancer Potential of Nano-betulinic Acid in Lung Cancer-

OBJECTIVES: This study examined the relative efficacies of a derivative of betulinic acid (dBA) and its poly (lactide- co-glycolide) (PLGA) nano-encapsulated form in A549 lung cancer cells in vivo and in co-mutagen [sodium arsenite (SA) + benzo]undefined[a]pyrene (BaP)]-induced lung cancer in mice i...

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Bibliographic Details
Published in:J Pharmacopuncture
Main Authors: Das, Jayeeta, Samadder, Asmita, Das, Sreemanti, Paul, Avijit, Khuda-Bukhsh, Anisur Rahman
Format: Artigo
Language:Inglês
Published: KOREAN PHARMACOPUNCTURE INSTITUTE 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887750/
https://ncbi.nlm.nih.gov/pubmed/27280048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3831/KPI.2016.19.005
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