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Squish and squeeze – the nucleus as a physical barrier during migration in confining environments

From embryonic development to cancer metastasis, cell migration plays a central role in health and disease. It is increasingly becoming apparent that cells migrating in three-dimensional (3-D) environments exhibit some striking differences compared with their well-established 2-D counterparts. One k...

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Detalhes bibliográficos
Publicado no:Curr Opin Cell Biol
Main Authors: McGregor, Alexandra Lynn, Hsia, Chieh-Ren, Lammerding, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887392/
https://ncbi.nlm.nih.gov/pubmed/26895141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2016.01.011
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