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Regulatory evolution of innate immunity through co-option of endogenous retroviruses

Endogenous retroviruses (ERVs) are abundant in mammalian genomes and contain sequences modulating transcription. How ERV propagation impacts the evolution of gene regulation remains poorly understood. Here we show that ERVs have shaped the evolution of a transcriptional network underlying the interf...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Chuong, Edward B., Elde, Nels C., Feschotte, Cédric
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887275/
https://ncbi.nlm.nih.gov/pubmed/26941318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad5497
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