Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics

A eubiotic microbiota influences many physiological processes in the metazoan host, including development and intestinal homeostasis. Here, we have shown that the intestinal microbiota modulates inflammatory responses caused by sex steroid deficiency, leading to trabecular bone loss. In murine model...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Li, Jau-Yi, Chassaing, Benoit, Tyagi, Abdul Malik, Vaccaro, Chiara, Luo, Tao, Adams, Jonathan, Darby, Trevor M., Weitzmann, M. Neale, Mulle, Jennifer G., Gewirtz, Andrew T., Jones, Rheinallt M., Pacifici, Roberto
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887186/
https://ncbi.nlm.nih.gov/pubmed/27111232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86062
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