A STAT6 Intronic Single-Nucleotide Polymorphism is Associated with Clinical Malaria in Ghanaian Children

Malaria pathogenesis may be influenced by IgE responses and cytokine cross-regulation. Several mutations in the IL-4/STAT6 signaling pathway can alter cytokine cross-regulation and IgE responses during a Plasmodium falciparum malarial infection. This study investigated the relationship between a STA...

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Veröffentlicht in:Genet Epigenet
Hauptverfasser: Amoako-Sakyi, Daniel, Adukpo, Selorme, Kusi, Kwadwo A., Dodoo, Daniel, Ofori, Michael F., Adjei, George O., Edoh, Dominic E., Asmah, Richard H., Brown, Charles, Adu, Bright, Obiri-Yeboah, Dorcas, Futagbi, Godfred, Abubakari, Sharif Buari, Troye-Blomberg, Marita, Akanmori, Bartholomew D., Goka, Bamenla Q., Arko-Mensah, John, Gyan, Ben A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Libertas Academica 2016
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887113/
https://ncbi.nlm.nih.gov/pubmed/27279750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/GEG.S38307
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