Ex Vivo and In Vivo Evaluation of Overexpressed VLA-4 in Multiple Myeloma Using LLP2A Imaging Agents

Very-late-antigen-4 (VLA-4, α(4)β(1) integrin, CD49d/CD29) is a transmembrane adhesion receptor that plays an important role in cancer and immune responses. Enhanced VLA-4 expression has been observed in multiple myeloma (MM) cells and surrounding stroma. VLA-4 conformational activation has been ass...

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Publicat a:J Nucl Med
Autors principals: Soodgupta, Deepti, Zhou, Haiying, Beaino, Wissam, Lu, Lan, Rettig, Michael, Snee, Mark, Skeath, James, DiPersio, John F., Akers, Walter J., Laforest, Richard, Anderson, Carolyn J., Tomasson, Michael H., Shokeen, Monica
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887080/
https://ncbi.nlm.nih.gov/pubmed/26742713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.164624
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