HMGB1 Induces Secretion of Matrix Vesicles by Macrophages to Enhance Ectopic Mineralization

Numerous clinical conditions have been linked to ectopic mineralization (EM). This process of pathological biomineralization is complex and not fully elucidated, but thought to be started within matrix vesicles (MVs). We hypothesized that high mobility group box 1 (HMGB1), a cytokine associated with...

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Udgivet i:PLoS One
Main Authors: Chen, Qiang, Bei, Jun-Jie, Liu, Chuan, Feng, Shi-Bin, Zhao, Wei-Bo, Zhou, Zhou, Yu, Zheng-Ping, Du, Xiao-Jun, Hu, Hou-Yuan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887028/
https://ncbi.nlm.nih.gov/pubmed/27243975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156686
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